Birthing feminist pragmatist epistemologies -- Feminist epistemologies -- Embodiment -- Project overview -- Quine's naturalized epistemology -- A brief history of objectivity in western philosophy -- Quine's empiricism -- Holism -- Ontological and epistemological impact -- Antony's analytic feminist empiricism -- Objectivity and the bias paradox -- Quine's naturalized epistemology solves bias paradox -- Anti-quinean realism -- Nelson's holistic feminist empiricism -- Nelson's holism -- Communities as knowers -- Facts/values -- Dewey's theory of inquiry -- Epistemology and inquiry -- Biological (...) and cultural matrices -- Habits and embodiment -- Feminist pragmatist inquiry -- OB/GYN and midwifery models -- Time -- Technology -- Spatial presence -- Tacit knowledge as feminist. (shrink)

Even as public health ethics was developing as a field, major incidents such as 9/11 and the SARS epidemic propelled discourse around public health emergency preparedness and response. Policy and practice shifted to a multidisciplinary approach, recognizing the broad range of potential threats to public health, including biological, physical, radiological, and chemical threats. This propelled the development of surveillance systems to detect incidents, laboratory capacities to rapidly test for potential threats, and therapeutic and social countermeasures to prepare for and respond (...) to a range of hazards. In bringing public health ethics and emergency preparedness together, Emergency Ethics: Public Health Preparedness and Response adds depth and complexity to both fields. As global threats continue to emerge, the book, edited by Bruce Jennings, John D. Arras, Drue H. Barrett, and Barbara A. Ellis, will offer a vital compass. (shrink)

Mouse embryonic stem cell lines offer an attractive route for introducing rare genetic alternations into the gene pool since the cells can be pre‐screened in culture and the mutations then transmitted into the germline through chimera production. Two applications of this technique seem ideally suited for a genetic analysis of development are enhancer and gene trap screens for loci expressed during gastrulation and production of targeted mutations using homologous recombination. These approaches should greatly increase the number of mouse developmental mutants (...) available and help to elucidate the genetic hierarchy controlling embryogenesis. (shrink)

Global health law for pandemics currently lacks legal obligations to ensure distributional and reparative justice. In contrast, international environmental law contains several novel international legal mechanisms aimed at addressing the effects of colonialism and global injustices that arise from the disproportionate contributions to — and impacts of — climate change and biodiversity loss.

The American Urological Association (AUA) and American College of Surgeons (ACS) codes of professionalism require surgeons to disclose the specific roles and responsibilities of trainees to patients during the informed consent process. The objective of this study is to analyze how these requirements are met by urology training programs. An anonymous electronic survey was distributed to the program directors (PDs) of the 143 Accreditation Council for Graduate Medical Education urology residency programs in the United States in 2021. Information was collected (...) regarding program demographics, aspects of the program’s consent process, and the disclosure to patients of the role and participation of residents in their surgery. There were 49 responses to the survey (34.3% response rate). Nearly 70 percent of PDs reported that attending physicians lead the consent process. The topics covered during consent discussion include possible complications (25%), expected recovery time (23%), length of the surgery (22%), the people involved (18%), and their specific roles (7%). Many PDs do not explicitly discuss trainee involvement (48.8%) or when a resident is to perform the majority of the case (87.8%). The majority of PDs (78.8%) communicate medical student involvement, but 73.2 percent reported having a patient decline participation of a trainee after describing their role. Despite the AUA and ACS codes of professionalism, many urologists do not disclose resident involvement in surgery to patients. Further discussions are needed to explore how to better balance resident education and patient autonomy. (shrink)

BackgroundWhen conducting research with Indigenous populations consent should be sought from both individual participants and the local community. We aimed to search and summarise the literature about methods for seeking consent for research with Indigenous populations.MethodsA systematic literature search was conducted for articles that describe or evaluate the process of seeking informed consent for research with Indigenous participants. Guidelines for ethical research and for seeking consent with Indigenous people are also included in our review.ResultsOf 1447 articles found 1391 were excluded (...) ; 56 were relevant and included. Articles were categorised into original research that evaluated the consent process or publications detailing the process of seeking consent and guidelines for ethical research. Guidelines were categorised into international ; national and state/regional/local guidelines. In five studies based in Australia, Canada and The United States of America the consent process with Indigenous people was objectively evaluated. In 13 other studies interpreters, voice recording, videos, pictures, flipcharts and “plain language” forms were used to assist in seeking consent but these processes were not evaluated. Some Indigenous organisations provide examples of community-designed resources for seeking consent and describe methods of community engagement, but none are evaluated. International, national and local ethical guidelines stress the importance of upholding Indigenous values but fail to specify methods for engaging communities or obtaining individual consent. In the ‘Grey literature’ concerns about the consent process are identified but no solutions are offered.ConclusionConsultation with Indigenous communities is needed to determine how consent should be sought from the community and the individual, and how to evaluate this process. (shrink)

The consent and community engagement process for research with Indigenous communities is rarely evaluated. Research protocols are not always collaborative, inclusive or culturally respectful. If participants do not trust or understand the research, selection bias may occur in recruitment, affecting study results potentially denying participants the opportunity to provide more knowledge and greater understanding about their community. Poorly informed consent can also harm the individual participant and the community as a whole. Invited by local Aboriginal community leaders of the Fitzroy (...) Valley, the Kimberley, Western Australia, The Picture Talk project explores the consent process for research. Focus groups of Aboriginal community members were conducted to establish preferences for methods of seeking individual consent. Transcripts were analysed through NVivo10 Qualitative software using grounded theory with inductive and deductive coding. Themes were synthesised with quotes highlighted. Focus groups with Aboriginal community members were facilitated by a Community Navigator as a cultural guide and interpreter and a researcher. Participants were recruited from all main language groups of the Fitzroy Valley – Gooniyandi, Walmajarri, Wangkatjungka, Bunuba and Nikinya. Participants were aged ≥18 years, with 5 female groups and one male group. Themes identified include: Reputation and trust is essential; The Community Navigator is key; Pictures give the words meaning – milli milli versus Pictures; Achieving consensus in circles; Signing for consent; and Research is needed in the Valley. Aboriginal communities of the Fitzroy Valley recommend that researchers collaborate with local leaders, develop trust and foster a good reputation in the community prior to research. Local Aboriginal researchers should be employed to provide cultural guidance throughout the research process and interpret local languages especially for elders. Pictures are preferred to written text to explain research information and most prefer to sign for consent. The Fitzroy Valley welcomes research when collaborative and for the benefit of the community. Future research could include exploring how to support young people, promote health screening and improve understanding of medical knowledge. (shrink)

This article identifies limitations in traditional approaches to engineering ethics pedagogy, reflected in an overreliance on disaster case studies. Researchers in the field have pointed out that these approaches tend to occlude ethically significant aspects of day-to-day engineering practice and thus reductively individualize and decontextualize ethical decision-making. Some have proposed, as a remedy for these defects, the use of research and theory from Science and Technology Studies to enrich our understanding of the ways in which technology and engineering practice are (...) intricated in social and institutional contexts. While endorsing this approach, this article also argues that STS scholarship may not sufficiently address the kinds of questions about normativity and agency that are essential to engineering ethics. It proposes making use of the growing body of research in a field called “postphenomenology,” an approach that combines STS research with the traditional phenomenological concern with the standpoint of lived-experience. Postphenomenology offers a method of inquiry that combines STS’s investigation into social and institutional dimensions of technology with phenomenological reflection on our lived experience of embodied engagement with technical objects and sociotechnical systems, particularly the ways in which these involvements affect our moral perception and agency. The aim in using this approach in engineering ethics is thus to illuminate moral dimensions of everyday professional life of which practitioners may not typically be aware. The article concludes with some concrete curricular interventions for engineering ethics classrooms. (shrink)

Name der Zeitschrift: Neue Zeitschrift für Systematische Theologie und Religionsphilosophie Jahrgang: 59 Heft: 1 Seiten: 1-25.

Perceptual learning involves an improvement in perceptual judgment with practice, which is often specific to stimulus or task factors. Perceptual learning has been shown on a range of visual tasks but very little research has explored chromatic perceptual learning. Here, we use two low level perceptual threshold tasks and a supra-threshold target detection task to assess chromatic perceptual learning and category effects. Experiment 1 investigates whether chromatic thresholds reduce as a result of training and at what level of analysis learning (...) effects occur. Experiment 2 explores the effect of category training on chromatic thresholds, whether training of this nature is category specific and whether it can induce categorical responding. Experiment 3 investigates the effect of category training on a higher level, lateralized target detection task, previously found to be sensitive to category effects. The findings indicate that performance on a perceptual threshold task improves following training but improvements do not transfer across retinal location or hue. Therefore, chromatic perceptual learning is category specific and can occur at relatively early stages of visual analysis. Additionally, category training does not induce category effects on a low level perceptual threshold task, as indicated by comparable discrimination thresholds at the newly learned hue boundary and adjacent test points. However, category training does induce category effects on a supra-threshold target detection task. Whilst chromatic perceptual learning is possible, learnt category effects appear to be a product of left hemisphere processing, and may require the input of higher level linguistic coding processes in order to manifest. (shrink)

Social networks play a significant role in learning and thus in farmers’ adoption of new agricultural technologies. This study examined the effects of social network factors on information acquisition and adoption of new seed varieties among groundnut farmers in Uganda and Kenya. The data were generated through face-to-face interviews from a random sample of 461 farmers, 232 in Uganda and 229 in Kenya. To assess these effects two alternative econometric models were used: a seemingly unrelated bivariate probit model and a (...) recursive bivariate probit model. The statistical evaluation of the SUBP shows that information acquisition and adoption decisions are interrelated while tests for the RBP do not support this latter model. Therefore, the analysis is based on the results obtained from the SUBP. These results reveal that social network factors, particularly weak ties with external support, partially influence information acquisition, but do not influence adoption. In Uganda, external support, gender, farm size, and geographic location have an impact on information acquisition. In Kenya, external support and geographic location also have an impact on information acquisition. With regard to adoption, gender, household size, and geographic location play the most important roles for Ugandan farmers, while in Kenya information from external sources, education, and farm size affect adoption choice. The study provides insight on the importance of external weak ties in groundnut farming, and a need to understand regional differences along gender lines while developing agricultural strategies. This study further illustrates the importance of farmer participation in applied technology research and the impact of social interactions among farmers and external agents. (shrink)

Objective Standards of care regarding obstetric management of life-threatening anomalies are not defined. It is hypothesised that physicians' management of these pregnancies is variable and influenced by demographic factors. Design A questionnaire was mailed to members of the Society of Maternal–Fetal Medicine with valid US addresses assessing obstetric management of both ‘uniformly lethal’ (eg, anencephaly, renal agenesis) and ‘uniformly severe, commonly lethal’ (eg, trisomy 13 and 18) anomalies. Respondents were asked to answer as if not limited by state/institutional restrictions. Fisher's (...) exact or χ2 tests were used as appropriate and correction made for multiple comparisons in analyses that were not prespecified. Results The response rate was 36% (732/2038). Nearly 100% of respondents discuss termination for both uniformly and commonly lethal anomalies. In continuing pregnancies, with patient request for obstetric non-intervention 99% of providers would comply for either uniformly or commonly lethal anomalies. The majority ‘encourage’ such management, but some were non-directive or discouraged this management. In continuing pregnancies, with patient request for full obstetric intervention the majority of respondents was willing to comply for both uniformly (71%) and commonly (82%) lethal anomalies. While most practitioners ‘discouraged’ full intervention, some were non-directive or encouraged this management. Demographics and severity of anomaly influenced counselling. Conclusion Discrepancies exist regarding the management of life-threatening fetal anomalies. Patients may be offered different options based on practitioner demographics. The majority of physicians comply with patient wishes. Differences were noted when comparing the management of lethal with that of severe commonly lethal anomalies, suggesting that practitioners make a distinction when counselling patients. (shrink)

Strengths, Opportunities, Aspirations, and Results is a strengths-based framework for strategic thinking, planning, conversations, and leading that focuses on strengths, opportunities, aspirations, and results. The SOAR framework leverages and integrates Appreciative Inquiry to create a transformation process through generative questions and positive framing. While SOAR has been used by practitioners since 2000 as a framework for generating positive organizational change, its use in empirical research has been limited by the absence of reliable and valid measures. We report on the reliability, (...) construct validity, and measurement invariance of the SOAR Scale, a 12-item self-report survey organized into four first-order factors. Data from a sample of 285 U.S. professionals were analyzed in Mplus using confirmatory factor analysis and exploratory structural equation modeling. The Four-Factor first-order exploratory structure equation modeling had the best model fit. Measurement invariance tests found the scalar invariance of the SOAR Scale across gender and education groups. Implications are discussed for using the SOAR Scale to build resilience at the individual, the team, and the organizational levels. (shrink)

Higher education, a key driver of women’s empowerment, is still segregated by gender across the world. Agricultural higher education is a field that is male-dominated, even though internationally women play a large role in agricultural production. The purpose of this study was to understand the experience, including challenges and coping strategies, of women from 10 Latin American countries attending an agricultural university in Latin America. The participants were 28 women students with a mean age of 20.9 ± 1.8 years. Following (...) informed consent and assurance of confidentiality, four focus group sessions (one for each year of study with a mean duration of 81 min) were conducted in Spanish. The central question was, “what has been your experience at the university?” Sessions were recorded and transcribed. Thematic coding was performed independently by two teams of researchers (from Latin America and North America), with the resulting schemas combined through mutual discussion. Member checking, auditing, and reflexivity contributed to trustworthiness of the process. Students reported that the personal qualities needed for success included determination, persistence, and self-efficacy. Many described an empowerment process, including increased discipline and self-efficacy from the first to fourth year of study. University life encompassed six themes: university structure and discipline (part of the exosystem), two supportive microsystems (friends and classmates and institutional support) as well as three challenges (academics, peers, and machismo). Cultural influences instantiated in students’ daily experiences included familism, machismo, and religious faith. Students anticipated futures involving further education and contributions to society. We conclude that higher education in agriculture can serve as an effective means of empowering women to feed the world. (shrink)

Common symptoms of multiple sclerosis include motor impairments of the lower extremities, particularly gait disturbances. Loss of balance and muscle weakness, representing some peripheral effects, have been shown to influence these symptoms, however, the individual role of cortical and subcortical structures in the central nervous system is still to be understood. Assessing [18F]fluorodeoxyglucose uptake in the CNS can assess brain activity and is directly associated with regional neuronal activity. One potential modality to increase cortical excitability and improve motor function in (...) patients with MS is transcranial direct current stimulation. However, tDCS group outcomes may not mirror individual subject responses, which impedes our knowledge of the pathophysiology and management of diseases like MS. Three PwMS randomly received both 3 mA tDCS and SHAM targeting the motor cortex that controls the more-affected leg for 20 min on separate days before walking on a treadmill. The radiotracer, FDG, was injected at minute two of the 20 min walk and the subjects underwent a Positron emission tomography scan immediately after the task. Differences in relative regional metabolism of areas under the tDCS anode and the basal ganglia were calculated and investigated. The results indicated diverse and individualized responses in regions under the anode and consistent increases in some basal ganglia areas. Thus, anodal tDCS targeting the M1 that controls the more-affected leg of PwMS might be capable of affecting remote subcortical regions and modulating the activity of the circuitry connected to these regions. (shrink)

As scientific and engineering efforts become increasingly global in nature, the need to understand differences in perceptions of research ethics issues across countries and cultures is imperative. However, investigations into the connection between nationality and ethical decision-making in the sciences have largely generated mixed results. In Study 1 of this paper, a measure of biases and compensatory strategies that could influence ethical decisions was administered. Results from this study indicated that graduate students from the United States and international graduate students (...) studying in the US are prone to different biases. Based on these findings, recommendations are made for developing ethics education interventions to target these decision-making biases. In Study 2, we employed an ethics training intervention based on ethical sensemaking and used a well-established measure of ethical decision-making that more fully captures the content of ethical judgment. Similar to Study 1, the results obtained in this study suggest differences do exist between graduate students from the US and international graduate students in ethical decision-making prior to taking the research ethics training. However, similar effects were observed for both groups following the completion of the ethics training intervention. (shrink)

As scientific and engineering efforts become increasingly global in nature, the need to understand differences in perceptions of research ethics issues across countries and cultures is imperative. However, investigations into the connection between nationality and ethical decision-making in the sciences have largely generated mixed results. In Study 1 of this paper, a measure of biases and compensatory strategies that could influence ethical decisions was administered. Results from this study indicated that graduate students from the United States and international graduate students (...) studying in the US are prone to different biases. Based on these findings, recommendations are made for developing ethics education interventions to target these decision-making biases. In Study 2, we employed an ethics training intervention based on ethical sensemaking and used a well-established measure of ethical decision-making that more fully captures the content of ethical judgment. Similar to Study 1, the results obtained in this study suggest differences do exist between graduate students from the US and international graduate students in ethical decision-making prior to taking the research ethics training. However, similar effects were observed for both groups following the completion of the ethics training intervention. (shrink)

The new National Institutes of Health (NIH) Policy on the Use of a Single Institutional Review Board (sIRB) for Multi-Site Research was adopted primarily to simplify and speed the review of complex multisite clinical trials. However, speeding review requires overcoming a number of obstacles. Perhaps the most substantial obstacle is the time and effort needed to develop reliance agreements among the participating sites. We conducted 102 semistructured interviews with sIRB personnel, including directors, chairs, reviewers, and staff, from 20 IRBs that (...) acted as sIRBs for multisite research, including 6 commercial/independent sIRBs, and 10 university-based academic and 4 federal sIRBs. Almost without exception, the interviewees agreed that reliance agreements were complex, difficult to develop, and time-consuming. A major problem for relying sites was that different agreements specified different responsibilities for the relying sites. Attitudes differed about whether these problems will be resolved as IRB staff and managers become more experienced with sIRBs. However it is clear that the process of developing reliance agreements must be simplified. Federal assistance in standardizing at least some sections of reliance agreements might reduce the difficulties involved. (shrink)

Pour ceux qui s'interrogent sur le fascisme d'Emil Cioran ou plus encore de Mircea Eliade, ce livre dissipera les derniers doutes. Loin du péché de jeunesse, on y découvrira, à partir d'écrits politiques inédits en français et d'archives jusque-là inexploitées, l'ampleur du plaidoyer antisémite et ultranationaliste porté par ces deux intellectuels aujourd'hui mondialement célèbres... mais aussi leur obstination à camoufler, voire à recycler après 1945, une filiation idéologique pourtant indispensable à l'intelligence des œuvres de la maturité. De cet " oubli (...) du fascisme ", Eugène Ionesco fut-il le témoin consentant? Le jeune intellectuel de gauche connaissait parfaitement, pour l'avoir combattu dans les années 30, l'engagement de ses deux compatriotes d'origine roumaine. Comment comprendre dès lors l'étrange pacte du silence scellé après-guerre entre les trois hommes? Amnésie complice ou effet équivoque des solidarités anticommunistes de l'exil? Cet essai, dont le ton n'est jamais inquisitoire, vient lézarder des pans entiers de notre culture en montrant comment la pensée d'un Eliade ou d'un Cioran a pu justifier une des dérives les plus meurtrières du XXe siècle. Au fil d'une enquête historique minutieuse, qui nous mènera du Bucarest de la Garde de fer à Paris, en passant par les refuges diplomatiques de la Seconde Guerre mondiale - où, entre Vichy et le Portugal de Salazar, on suivra les trois écrivains en poste dans diverses ambassades d'un pays allié du Ille Reich -, Alexandra Laignel-Lavastine éclaire la face trop longtemps cachée de leurs trajectoires. D'où les deux versants de cette triple biographie intellectuelle qui analyse ensuite avec brio le succès des multiples stratégies sociales et littéraires mises en œuvre pour dissimuler un passé devenu soudain très encombrant. (shrink)

This paper proposes a new approach to Augustine’s illumination theory, understanding illumination as resulting from an act of the human being as much as from an action of God. Regardless of God’s ever present light, the human intellect is not constantly and indiscriminately illuminated. In order to explain how the human intellect attains knowledge to different degrees, and how it can resist the divine light without being actually able to deny it, I will make use of two concepts Augustine himself (...) did not employ : the first one is relationship, the second, referring to God, is being-for-others. As being-for-others, God gives the human being not the gift of knowledge, but that of the relationship with Him (as Truth and Wisdom), by means of which the human being can attain knowledge. By placing Himself in relationship with the human being, God grants it the freedom and power to cooperate in divine actions : re-creation after the fall (formatio), illumination and salvation. If passive, the human intellect does not receive knowledge, it is only in its turning towards the ever present light of Truth that it sees the intelligible truths in the divine light, and it is able to do so to the extent of one’s good will, or one’s love (caritas). Augustine sees illumination as a joint action of God and human being, depending on human being no less than on God. The concept of relationship and the understanding of God as being-for-others explain why no illumination will take place without the active role of the human intellect, why the divine light is not coercive, and why Augustine considers the necessity of both human freedom and God’s power in the act of knowledge. (shrink)

This paper proposes a new approach to Augustine’s illumination theory, understanding illumination as resulting from an act of the human being as much as from an action of God. Regardless of God’s ever present light, the human intellect is not constantly and indiscriminately illuminated. In order to explain how the human intellect attains knowledge to different degrees, and how it can resist the divine light without being actually able to deny it, I will make use of two concepts Augustine himself (...) did not employ : the first one is relationship, the second, referring to God, is being-for-others. As being-for-others, God gives the human being not the gift of knowledge, but that of the relationship with Him (as Truth and Wisdom), by means of which the human being can attain knowledge. By placing Himself in relationship with the human being, God grants it the freedom and power to cooperate in divine actions : re-creation after the fall (formatio), illumination and salvation. If passive, the human intellect does not receive knowledge, it is only in its turning towards the ever present light of Truth that it sees the intelligible truths in the divine light, and it is able to do so to the extent of one’s good will, or one’s love (caritas). Augustine sees illumination as a joint action of God and human being, depending on human being no less than on God. The concept of relationship and the understanding of God as being-for-others explain why no illumination will take place without the active role of the human intellect, why the divine light is not coercive, and why Augustine considers the necessity of both human freedom and God’s power in the act of knowledge. (shrink)

La problématisation freudienne de l’expérience ne consiste pas à s’interroger, de manière classique, sur la façon dont le sujet constitue en un savoir objectif des événements particuliers, mais comment le sujet lui-même est constitué en une identité objective, c’est-à-dire dont il peut avoir une connaissance consciente et qui peut être reconnue comme telle par d’autres, à partir d’événements singuliers qui se produisent dans un contexte en-deçà du champ théorique de la conscience, celui du plaisir. S’il part ainsi d’une problématique empiriste (...) de l’expérience (comment, dans le donné, peut-il se constituer un sujet tel qu’il dépasse le donné ?), il estime qu’il faut également chercher à comprendre, à partir de l’expérience elle-même en tant que vécu, la nécessité du rapport entre expérience et subjectivité : si c’est l’expérience qui « produit » le sujet, celui-ci faisant alors figure de dérivé ou d’ « épiphénomène », comment comprendre la « nécessité » de cette production, ainsi que le fait que, une fois constitué, le sujet se définit en retour comme un élément essentiel à l’expérience ? Le sujet de l’expérience ne fait-il que répéter indéfiniment des événements originaires dont le sens lui échappe, ou participe-t-il effectivement à la réalité des expériences qui l’affectent ? (shrink)

Au tournant des années 1820-1830, Schelling découvre au sein de la philosophie deux grandes tendances à l'oeuvre : une tendance "négative" à rendre intelligible le réel en fonction de la nécessité des lois de la pensée, une tendance "positive" à y voir au contraire le fait d'un acte libre. Scrutant cette différence, il finit par montrer qu'elle implique de scinder la philosophie même en une philosophie qui fait intervenir uniquement la raison et une philosophie où la raison se laisse instruire (...) par l'expérience. Le présent livre propose une interprétation nouvelle de ce moment crucial mais méconnu de la pensée moderne où Schelling accomplit, tout en le dépassant, l'idéalisme allemand. On y montre qu'il suspend l'avenir de la raison à un dédoublement de la philosophie qui implique de confier la réalisation des deux philosophies à un rationalisme et à un empirisme totalement inédits. Dans le rationalisme, la raison opère seule jusqu'à produire l'idée d'un principe absolu libre de poser le monde ; dans l'empirisme, elle prouve l'existence du principe par ses oeuvres effectives que sont successivement les faits de la nature et ceux de la conscience comme conscience religieuse. Ainsi, loin de produire le désespoir de la raison, Schelling montre au contraire que la raison se donne à elle-même un avenir en se différenciant. (shrink)

BackgroundThe ARRIVE (Animal Research: Reporting of In Vivo Experiments) guidelines are widely endorsed but compliance is limited. We sought to determine whether journal-requested completion of an ARRIVE checklist improves full compliance with the guidelines.MethodsIn a randomised controlled trial, manuscripts reporting in vivo animal research submitted to PLOS ONE (March–June 2015) were randomly allocated to either requested completion of an ARRIVE checklist or current standard practice. Authors, academic editors, and peer reviewers were blinded to group allocation. Trained reviewers performed outcome adjudication (...) in duplicate by assessing manuscripts against an operationalised version of the ARRIVE guidelines that consists 108 items. Our primary outcome was the between-group differences in the proportion of manuscripts meeting all ARRIVE guideline checklist subitems.ResultsWe randomised 1689 manuscripts (control: n = 844, intervention: n = 845), of which 1269 were sent for peer review and 762 (control: n = 340; intervention: n = 332) accepted for publication. No manuscript in either group achieved full compliance with the ARRIVE checklist. Details of animal husbandry (ARRIVE subitem 9b) was the only subitem to show improvements in reporting, with the proportion of compliant manuscripts rising from 52.1 to 74.1% (X2 = 34.0, df = 1, p = 2.1 × 10−7) in the control and intervention groups, respectively.ConclusionsThese results suggest that altering the editorial process to include requests for a completed ARRIVE checklist is not enough to improve compliance with the ARRIVE guidelines. Other approaches, such as more stringent editorial policies or a targeted approach on key quality items, may promote improvements in reporting. (shrink)

Résumé La présente étude aborde la notion de « changement » dans le cadre de la cité grecque de l’époque classique, mais du côté opposé, celui de la continuité historique. Pour ce faire, elle examine les mots et expressions désignant le passé ancestral d’un peuple : elle étudie les significations du terme patrios et des termes apparentés dans la littérature grecque des Ve et IVe siècles, présente le cadre politique dans lequel les générations qui vivent à l’époque classique font appel (...) à leurs ancêtres et recherche, enfin, les éléments qui construisent l’identité de la cité classique. D’abord, il en ressort que les notions d’« ancestral » et de « traditionnel » sont floues et que leur connotation dépend des individus qui en font usage, ainsi que du moment historique dans lequel vivent les intéressés. Ensuite, il apparaît qu’elles sont le moyen qui permet aux Anciens d’exprimer leur réaction – positive ou négative – face aux transformations multiples que subissent les sociétés classiques. (shrink)

Les approches classiques de l'engagement se sont principalement intéressées à ses déterminants, rapportés à des variables sociodémographiques, des dispositions, des vertus ou des rétributions, comme à autant de motifs déjà constitués en amont et extrinsèques à l'expérience de l'engagement. Or, les intérêts des personnes - et leur puissance d'agir elle-même - peuvent s'analyser comme des produits de l'engagement, pour peu qu'on le saisisse dans sa dimension temporelle, itérative et située. Envisagé comme expérience, il paraît indissociable d'une enquête menée à la (...) fois sur soi et sur le monde, où les personnes interrogent autant leurs propres désirs et possibilités d'agir, que la vie commune qu'elles souhaitent cultiver ou voir advenir. Ce volume rassemble une série de contributions théoriques et empiriques qui explorent des façons d'articuler souci de soi et souci du monde. Elles documentent la façon dont les engagements circulent entre différentes sphères de la vie et entre moments biographiques, en suivant les formes d'expérimentation auxquelles ils donnent lieu. Notre compréhension du rapport au politique s'en trouve enrichie, ressaisie depuis la trame des expériences de la vie commune faites en personne"--Page 4 of cover. (shrink)

Health care professionals assigned to critical care are confronted on a daily basis with particularly trying situations. Their hard work conditions can become anxiety-provoking, affect their physical and/or psychological condition, decrease their performance and increase their absenteeism rate at work. To face this particularly stressful and sometimes depressing context, some professionals fall back on “gallows humour”, a sort of black humour with a morbid overtone, which is likely to shock certain people. Although gallows humour is very widespread, its use in (...) critical care is extremely controversial and most of the time reprimanded by professional orders. Based on the codes of ethics that govern them, professional orders assume that gallows humour violates the duties and responsibilities of their members towards their patients, rejecting its use straightaway. In this article, we contest the categorical rejection of gallows humour in critical care. We adopt a consequentialist perspective based on the study of scientific literature on the benefits of using humour in the workplace, to defend its ethical acceptability. By enabling us to be better prepared to provide care despite the tragic events experienced by professionals, we will see how the use of gallows humour can ultimately have a positive effect on patients. A consequentialist ethics is not only interested in maximizing the benefits of gallows humour but also in reducing the risk of harm to others related to its use. This important criterion will therefore lead us to define the terms and suggest certain conditions that must be respected for an ethical use of this important defense mechanism by health care professionals in critical care. (shrink)

Health care professionals assigned to critical care are confronted on a daily basis with particularly trying situations. Their hard work conditions can become anxiety-provoking, affect their physical and/or psychological condition, decrease their performance and increase their absenteeism rate at work. To face this particularly stressful and sometimes depressing context, some professionals fall back on “gallows humour”, a sort of black humour with a morbid overtone, which is likely to shock certain people. Although gallows humour is very widespread, its use in (...) critical care is extremely controversial and most of the time reprimanded by professional orders. Based on the codes of ethics that govern them, professional orders assume that gallows humour violates the duties and responsibilities of their members towards their patients, rejecting its use straightaway. In this article, we contest the categorical rejection of gallows humour in critical care. We adopt a consequentialist perspective based on the study of scientific literature on the benefits of using humour in the workplace, to defend its ethical acceptability. By enabling us to be better prepared to provide care despite the tragic events experienced by professionals, we will see how the use of gallows humour can ultimately have a positive effect on patients. A consequentialist ethics is not only interested in maximizing the benefits of gallows humour but also in reducing the risk of harm to others related to its use. This important criterion will therefore lead us to define the terms and suggest certain conditions that must be respected for an ethical use of this important defense mechanism by health care professionals in critical care. (shrink)

In the United States, final amendments to the Federal Policy for the Protection of Human Subjects (“the Common Rule”) were published on January 19, 2017, and they will take effect on January 21, 2019. One of the most widely discussed provisions is that for the first time, federal regulations governing research with humans authorize the use of broad consent for future, unspecified research on individually identifiable biospecimens and associated data. Many questions have been raised about broad consent, including what effect (...) it will have on research and whether it adequately protects the interests of research participants.There are lessons to be learned for the U.S. and other countries by looking to countries that already have experience with broad consent for biobank collection and with the storage and subsequent use of the biospecimens and data. This article describes how broad consent works in five countries—Canada (in Quebec), Israel, Nigeria, Taiwan, and the United Kingdom—and with different types of biobanks: national biobanks, federated biobanks, and regional biobanks. Evaluating the provisions and challenges of the broad consent approaches in these countries can inform policies for this increasingly used approach to biobank regulation. (shrink)

Ce volume, qui comporte six études d’Étienne Évrard, a le grand mérite de rendre pour la première fois accessible deux inédits du grand spécialiste de Philopon qui enseigna le latin pendant près de trente ans à l’Université de Liège. Le projet de Marc-Antoine Gavray de consacrer un volume au travail d’É. Évrard résulte, comme il l’indique lui-même avec enjouement dans son introduction, d’une sorte de hasard bienvenu : l’inondation soudaine du fonds du magasin à livres de l’ULg, au milieu des...

© 2017. The American Astronomical Society. All rights reserved.We present new observations of the low-mass companion to HD 984 taken with the Gemini Planet Imager as a part of the GPI Exoplanet Survey campaign. Images of HD 984 B were obtained in the J and H bands. Combined with archival epochs from 2012 and 2014, we fit the first orbit to the companion to find an 18 au orbit with a 68% confidence interval between 14 and 28 au, an eccentricity (...) of 0.18 with a 68% confidence interval between 0.05 and 0.47, and an inclination of 119°with a 68% confidence interval between 114°and 125°. To address the considerable spectral covariance in both spectra, we present a method of splitting the spectra into low and high frequencies to analyze the spectral structure at different spatial frequencies with the proper spectral noise correlation. Using the split spectra, we compare them to known spectral types using field brown dwarf and low-mass star spectra and find a best-fit match of a field gravity M6.5 ±1.5 spectral type with a corresponding temperature of K. Photometry of the companion yields a luminosity of log=2.88 ± 0.07 dex with DUSTY models. Mass estimates, again from DUSTY models, find an age-dependent mass of 34 ±1 to 95 ±4 M Jup. These results are consistent with previous measurements of the object. (shrink)

Interaction analysis opens promising perspectives for nursing education. Sixteen students and three teachers conducted an interaction analysis, based on video-recorded therapeutic activities. The study aims to understand the practice of self-disclosure in psychiatric nursing. How does the use of interaction analysis tools in a training setting constitute a resource for the acquisition of professional skills? We show how this training design constitutes a resource for : a) the acquisition of clinical theoretical knowledge, b) the articulation of theoretical and practical knowledge, (...) c) the development of a non-judging descriptive posture useful for the clinical observation. (shrink)

Cet article a déjà paru dans Techniques & Culture en ligne, 48-49 | 2007 Résumé : L'œuvre d'André Leroi-Gourhan est traversée par une anthropologie du rythme. Celle-ci ne part pas d'une socialité constituée, de rythmes dits « sociaux », mais inscrit au contraire l'analyse de la rythmicité dans une approche de l'homme comme être vivant, comme totalité indivise. Elle pose en des termes renouvelés le problème classique du groupement des hommes et des liens entre l'individu et son milieu. Avec la (...) question - Anthropologie. (shrink)

Résumé La théologie de Numénius, qui définit le premier dieu comme un principe totalement simple, solitaire et transcendant, a joué un grand rôle dans la construction de l’hénologie plotinienne. Or, si cette dernière est en partie héritière des réflexions médioplatoniciennes, elle marque également un véritable tournant dans l’histoire du platonisme. Tandis que le premier principe de Numénius exprime l’unité parfaite de l’être et de l’intellect, l’Un de Plotin est « au-delà de l’être » de manière absolue. Cette différence a des (...) conséquences décisives, tant sur la manière de concevoir le rapport du premier au second principe, que sur l’interprétation de la relation de l’Intellect divin à son objet. Cet article se propose d’analyser, à travers une étude de la conception du premier principe chez Plotin et Numénius, l’apport métaphysique que représente l’existence d’un principe au-delà de l’être. (shrink)

"L'idée de cet ouvrage prend sa source dans un texte du tout dernier Schelling, extrait de l'Exposé de la philosophie rationnelle pure, professé à Berlin dans les années 1847-1852 et publié ensuite par le fils de Schelling dans un ensemble plus vaste, l'Introduction à la Philosophie de la mythologie."--Prologue, p. [7].

© The Author 2016. Published by Oxford University Press on behalf of Japanese Society of Plant Physiologists. All rights reserved.Cell walls of grasses, including cereal crops and biofuel grasses, comprise the majority of plant biomass and intimately influence plant growth, development and physiology. However, the functions of many cell wall synthesis genes, and the relationships among and the functions of cell wall components remain obscure. To better understand the patterns of cell wall accumulation and identify genes that act in grass (...) cell wall biosynthesis, we characterized 30 samples from aerial organs of rice at 10 developmental time points, 3-100 d post-germination. Within these samples, we measured 15 cell wall chemical components, enzymatic digestibility and 18 cell wall polysaccharide epitopes/ligands. We also used quantitative reverse transcription-PCR to measure expression of 50 glycosyltransferases, 15 acyltransferases and eight phenylpropanoid genes, many of which had previously been identified as being highly expressed in rice. Most cell wall components vary significantly during development, and correlations among them support current understanding of cell walls. We identified 92 significant correlations between cell wall components and gene expression and establish nine strong hypotheses for genes that synthesize xylans, mixed linkage glucan and pectin components. This work provides an extensive analysis of cell wall composition throughout rice development, identifies genes likely to synthesize grass cell walls, and provides a framework for development of genetically improved grasses for use in lignocellulosic biofuel production and agriculture. (shrink)